Specifically, it is essential to elucidate how SCF modulates the gut microbiota and whether microbial metabolites such as short-chain FAs and bile acids mediate its therapeutic effects
In addition to its role in lipid metabolism, LC is implicated in amino acid metabolism, namely the transamination of branched-chain amino acids (BCAAs) such as leucine, isoleucine, and valine
Source: Hwang, et al JAMA Health Forum March 14, 2025 Researchers from the University of Chicago modeled the clinical and financial impact of anti-obesity medications: Zepbound (tirzepatide), Wegovy (semaglutide), and two oral generic drug combinations, phentermine-topiramate and naltrexone-bupropion
Over time, lower food intake can lead to gaps in key nutrients like protein, vitamins, and hydration
"The microscopic mites living in our oil glands and hair follicles play a role here," says Zeichner