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At Prescription Weight Loss, we believe education is empowering
As the takeup of these drugs, acquired via both the NHS and off-label prescriptions, continues on an ever-upward trajectory, more concerns are being raised about potential long-term side effects
To demonstrate the advantages of bivalent target binding through the full IgG format for enhancing avidity and selectivity, compared to most clinically approved bispecific T cell engagers that rely on monovalent binding, we introduced mutations (H91A and Y92A) in the complementarity-determining regions of Her2 to generate Her2 variants with reduced target binding affinity
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