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For Zepbound, this would be in combination with a reduced-calorie diet and increased physical activity, to reduce excess body weight and maintain weight reduction long term in obese or overweight adults in the presence of at least one weight-related comorbid condition and to treat moderate to severe obstructive sleep apnea in adults with obesity for weight management

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In patients who were prescribed these medications, researchers looked for adverse events involving the skin and hair by looking for the terms rash, pruritus, urticaria, alopecia, angioedema. Up to 8.16% of GLP-1 receptor agonists cases reported a cutaneous adverse event, most often in females

Think of it like filling a swimming pool with a garden hose