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It works by: Suppressing appetite signals in the hypothalamus (brain) Slowing gastric emptying food moves more slowly from your stomach to your intestine Stimulating insulin release and reducing glucagon production Stabilizing post-meal blood sugar levels Slowing gastric emptying is the primary driver of most gastrointestinal (GI) side effects

In practice, 'stacking' is a term borrowed from performance and supplement culture rather than clinical pharmacology, and it simply means using two agents together in the hope of an additive or synergistic effect

Matthews DR, Paldnius PM, Proot P, Chiang Y, Stumvoll M, Del Prato S

The most important caveat is regulatory and scientific: the U.S

Furthermore, it is easily dissolved in water and needs no carrier for its application