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Eder J, Prillinger K, Korn A, Geroldinger A, Trautinger F
Longer-term safety questions including effects on the pancreas, thyroid, gallbladder, and cardiovascular system remain under investigation in ongoing Phase 3 trials
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Prescription of guideline-directed medical therapies in patients with diabetes and chronic kidney disease from the CURE-CKD Registry, 2019-2020
That same body of work also shows meaningful weight outcomes: in one study of 500 patients, 75% reported significant weight loss with semaglutide, and these changes drive downstream shifts in lipids and cardiovascular markers
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