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doi: 10.1097/00004872-200306000-00012 94 KatsuradaKNakataMSaitoTZhangBMaejimaYNandiSSet al
It has been hypothesized that a reduction in hepatic GCGR and signaling molecules affects a feedback mechanism acting on the pancreatic alpha cells, increasing glucagon secretion, and this liver-pancreas axis might contribute to fasting hyperglucagonemia (36)
Processed and Sugary Foods Highly processed foods and those loaded with refined sugar increase oxidative stress in the body
Slower dose escalation or short treatment pauses may improve tolerance 9,15
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