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Paleolithic nutrition revisited: a twelve-year retrospective on its nature and implications

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*In a 68- and 72-week clinical trial studying Wegovy (2.4 mg) in patients without diabetes and with BMI 30, or BMI 27 with a weight-related condition, the average weight loss was 15% and 20%, when paired with diet and exercise changes (compared to 2.4% and 3.1%, respectively, with diet and exercise alone)

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Therefore, when LDL-C and ApoB levels are discordant despite optimal lipid-lowering therapy, ApoB-targeted treatment targeting may be warranted

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Managing these side effects through gradual dose adjustments, smaller meals, staying hydrated, and avoiding trigger foods can help reduce discomfort and improve energy levels

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