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Increased NNMT activity has been observed in several metabolic research models and is associated with altered energy expenditure and disrupted NAD+ recycling
Regarding the form of vitamin B12 used, cyanocobalamin was the most common (n = 14), followed by methylcobalamin (n = 6), hydroxocobalamin (n = 4), and combinations including adenosylcobalamin in isolated cases
When levels are low, it can lead to persistent fatigue, weakness, and lack of motivation
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