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Setting The study was conducted using electronic health records from the US Department of Veterans Affairs, the largest integrated healthcare system in the US, consisting of 170 medical centres and 1193 outpatient clinics.22232425 All enrolled veterans received a comprehensive package of medical benefits, including prescription coverage for GLP-1 receptor agonists

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The key difference is mechanism: semaglutide acts on a single hormone pathway (GLP-1), while tirzepatide acts on two (GIP and GLP-1)

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