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The data showed adverse event rates of "well under 0.1%," he added

Combine resistance training at least three times weekly with daily protein intake of 0.7-1.0 grams per pound of body weight and a moderate caloric deficit of 20-25% below maintenance

Others step up to 0.125 or 0.15 mg to push results further

[1] [2] Persistent or severe symptoms may warrant dose reduction, temporary treatment interruption, or consideration of alternative therapeutic options