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Route is not a minor detail
While bloating alone rarely necessitates medication discontinuation, persistent severe symptoms warrant thorough evaluation to exclude serious pathology and optimize the treatment regimen
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In this instance, it may be helpful to eat several small meals, made up of healthy foods, throughout the day instead of typical larger ones
Most community protocols use a 24-week staggered titration to reach maintenance, then run open-ended at maintenance with periodic re-evaluation
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