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Drug Class & example SGLT2 inhibitors Empagliflozin 10 mg once daily Dapagliflozin 10 mg once daily Reduces HF hospitalizations, improves quality of life GLP-1 receptor agonist (oral) Semaglutide (Rybelsus) 714 mg once daily Start 3 mg daily 30 days, then 714 mg daily Promotes weight loss Glycemic and cardiac function improvement Mineralocorticoid receptor antagonists (MRAs) Spironolactone 12.525 mg daily Eplerenone 2550 mg daily Finerenone 1020 mg daily Manage potassium Reduce HF hospitalizations and fibrosis