Mazaheri, This is because when youre on the medication, your appetite is so small that you may not take in enough calories
Fat tissue plays an active role in oestrogen production, so a rapid reduction in body fat can lower circulating oestrogen levels, disrupting the hormonal signals that regulate the menstrual cycle
Your choice depends on whether you're prioritizing healing, fat loss, muscle gain, longevity, or performance
However, larger, longer-term studies are necessary to confirm these effects
MC4R activation promotes increased energy expenditure through stimulation of sympathetic nervous system activity, brown adipose tissue thermogenesis, and enhanced fatty acid oxidation