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Medicines with a narrow therapeutic index where small changes in blood concentration can have significant clinical consequences merit particular attention
Notably, each individual mutant exhibited a comparable phenotype, characterized by an approximate 12-fold reduction in survival, while still maintaining a residual ability to endure H 2 O 2 exposure
Metformin remains widely used due to its affordability and long safety record
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That long-term option is especially important for people whove struggled with yo-yo dieting or with regaining lost weight
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