Mechanism-based intervention potentially slowing progression
When toxic exposure, gut-derived inflammation, low zinc, oxidative stress, low SAM or elevated SAH exceed the livers metabolic reserve, detoxification may become less efficient and contribute to fatigue, brain fog, mood symptoms and toxic overload
A post hoc power calculation showed that the power was excellent (power = 1.0 based on alpha = 0.05, n = 25, mean in the morning = 95.7, mean in the evening = 86.4, standard deviation (SD) of the difference = 8.7 for paired samples)
This is particularly beneficial among severely dehydrated patients, who have difficulty absorbing nutrients through their digestive system or require rapid replenishment after intense physical activity or illness
5i, j, cell migration was elevated in all treatment groups relative to the control