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Semaglutide doesnt normally cause significant weight loss over a short period

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We acknowledge that classification of gastrointestinal AEs, such as nausea, vomiting, diarrhea, constipation, dyspepsia, and reduced appetite, may vary across studies, which could introduce some heterogeneity in the reported incidences

This mechanism reduces the risk of hypoglycaemia when used alone, though this risk increases significantly when combined with insulin or sulphonylureas