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[39] In animals, sodium valproate raises cerebral and cerebellar levels of GABA, possibly by inhibiting GABA degradative enzymes, such as GABA transaminase, succinate-semialdehyde dehydrogenase and by inhibiting the re-uptake of GABA by neuronal cells

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Short courses of anti-inflammatory medication Short courses of non-steroidal anti-inflammatory medication, when appropriate for the patient, can typically reduce knee pain and swelling