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A weekly clinic visit anchors accountability, the B12 corrects any genuine deficiency, and the nutrient load is unlikely to harm at typical volumes

improves insulin sensitivity and glycemic control

We identify mitochondrial trifunctional protein- (MTP) as a binding partner of GLP-1(2836) and demonstrate that the ability of GLP-1(2836) to shift substrate utilization from oxygen-consuming fatty acid metabolism toward oxygen-sparing glycolysis and glucose oxidation and to increase cAMP levels is dependent on MTP

The protocol was reviewed and approved by the Mercy Health Youngstown Institutional Review Board (IRB2023-137), and written informed consent was obtained from all participants before enrollment

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