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The primary objective was to demonstrate superiority of semaglutide 7.2 mg against placebo on weight loss after 72 weeks with respect to the percentage change in body weight and the proportion of participants achieving weight loss of 5% or greater
This is particularly significant for those with diabetes, as they face an elevated risk for heart conditions
This perspective critically considers those concerns and discusses the role of ADE more generally
Gastrointestinal side effects are the most frequently reported and include nausea, vomiting, diarrhoea, constipation, and abdominal discomfort
Cells were transfected at 80% confluency using Lipofectamine 2000 (Thermofisher) Briefly, 2 g pcDNA3.2- aptf2::V5 was diluted in 200 l Opti-MEM (Life Technologies) and 8 l Lipofectamine was diluted in 200 l Opti-MEM
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