In contrast to Hsp60, whose non-inducible IEC-specific knockout (using Villin1 Cre transgenic mice) is embryonic lethal (64), ClpP IEC mice are viable and exhibit normal growth and body weight development on a standard chow diet (data not shown), indicating less severe mitochondrial impairment
Treatment duration varies based on individual response, tolerability, and treatment goals, though many patients require long-term or indefinite therapy to maintain benefits
It has a half-life of five to seven days and requires a once-weekly injection
Glutathione bo v da khi c t, ngn nga vt thm v mn, ng thi loi b mi tp cht, mang li cho bn ln da trng sng v rng r hn
The distribution of men and women was similar between groups ( 2 = 3.36, df = 3, p = 0.33)