TRIUMPH-Outcomes enrolled adults with chronic kidney disease or atherosclerotic cardiovascular disease with obesity, a body mass index (BMI) of 27 or higher
The wide range of muscle loss seen in GLP-1 studies is likely due to differences in how body composition is measured, the type of participants studied, and factors like diet, activity level, and rate of weight loss
This meta-analysis reviews the efficacy of Adderall in treating ADHD, providing a synthesis of various clinical trials
For researchers tracking this space, the key trials to watch in 2026 include the remaining TRIUMPH program readouts for retatrutide, the GLORY-OSA trial for mazdutide in obstructive sleep apnea, and the first Phase 1 data from several quadruple-agonist programs entering clinical development
That means weekly shots are often needed in the beginning to keep energy and mood consistently up