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The main difference is how your body absorbs them: While the shots inject medication directly into your bloodstream, the pills have to go through your digestive system, explained Su-Nui Escobar, DCN, RDN, founder of Nutrition for Weight Loss Meds

Think of it like filling a bucket: its easier to keep it full if you plug the holes at the bottom

Safe Daily Dosage Guide Effervescent or peptide-based formats often improve absorption, allowing effective results at lower or standard doses

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