By occupying GLP-1 receptors in the brain, the medication promotes insulin release, slows gastric emptying, reduces glucagon secretion from the liver, and affects the hunger control centre (lateral hypothalamus) of the brain to suppress appetite
(PubMed) Rhodes A, Evans LE, Alhazzani W, et al
Telemedicine platforms that specialize in GLP-1 medications can connect you with a provider and ship your prescription directly to your door
Its weight-related effects are more modest and occur through: Reducing hepatic glucose production, which lowers circulating insulin levels Improving insulin sensitivity in peripheral tissues Potentially affecting appetite regulation Modest reduction in intestinal glucose absorption Metformin typically produces weight loss of 23 kg on average, or may prevent the weight gain often associated with other diabetes medications
Your GP or diabetes specialist will monitor your blood pressure regularly and may adjust your blood pressure medications if needed, particularly if your readings improve significantly