Here is what happens when NNMT is overactive: Your cells store more fat and burn less energy NAD+ levels drop (a critical molecule for energy production and cellular health) Insulin sensitivity decreases (making it harder to control blood sugar) Inflammation increases in fat tissue Metabolism slows down According to research in PMC, NNMT expression is upregulated in the white adipose tissue of obese and diabetic mice
However, sometimes due to other health conditions or food preferences, this isnt always possible, but if you can, you should consume foods that provide this valuable vitamin
The key difference is dosing range
For gastrointestinal conditions specifically, some clinicians use oral capsules, since the peptide acts directly on the gut lining
Cardiovascular Protection Studies Research reveals comprehensive cardiac protection including prevention of heart failure, normalization of elevated endothelin levels, and reduced long-term effects following myocardial infarction