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Systematically profiling the perturbations induced by DON exposure, including ubiquitination, phosphorylation, and other post-translational modifications, alongside genomic, epigenomic, and metabolomic alterations, will be crucial to mapping its comprehensive toxicological network and identifying additional key pathogenic nodes

Results X-ray crystal structure of PGRMC1 We solved the crystal structure of the haem-bound PGRMC1 cytosolic domain (a.a.72195) at 1.95 resolution (Supplementary Fig

Brain Function

weighted UniFrac: R value = 0.190, p = 0.0240

The triad model captures the OCR data for all concentrations of doxorubicin, simulating auto-oxidation via the formation of SQ . and O 2 . intermediates, which is in good accordance with the literature 3