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So people at greatest risk for deficiency include those with low stomach acid (e.g., older adults and people on proton pump inhibitors or antacids) or low IF production (known as pernicious anemia), people on medications that interfere with B12 absorption (such as metformin), people who have had gastric surgery, those with GI conditions that impair nutrient absorption (like celiac or Crohn's disease), and people on vegan and vegetarian diets

The process requires drawing the correct amount of water into a syringe, slowly injecting it into the vial, and gently swirling until the powder dissolves completely without shaking

Bimagrumab has the potential of improving the WL quality by preserving lean mass and could become an attractive treatment option for sarcopenic obesity