In line with this finding, GH receptor deficient mice have reduced relative liver weight[94], and transgenic mice overexpressing GH presented disproportional growth of the liver, whereas this is less apparent in mice overexpressing IGF-I[95, 96]
Toxicology (2012) 302(1):403
Although significant differences in protein levels were not found between the UFMs in the current analyses, the observation from the larger validation cohort measured by Zhi et al (1139 type 1 diabetic individuals and 848 control individuals) may have benefited from the improved statistical power
Kitakata H, Endo J, Matsushima H, Yamamoto S, Ikura H, Hirai A, et al
Ozdinler PH, Macklis JD: IGF-I specifically enhances axon outgrowth of corticospinal motor neurons