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329,330 In degenerative joint diseases like OA, the metabolic balance of chondrocytes is disrupted, leading to the overproduction of degrading enzymes and inflammatory mediators, including iNOS, MMP-13, and ADAMTS5 (a disintegrin and metalloproteinase with thrombospondin motifs 5), which participate in cartilage degradation and inflammatory processes
Liu T, and Su B
Some formulations of sodium chloride 0.9% may also contain preservatives for multi-dose use, while others are preservative-free single-use vials
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