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Hydrate Well: Drink plenty of water to help minimize potential side effects like flushing and headaches

It has also been observed a correlation between high levels of GSTP1-1 in the brain and medical intractability, suggesting that the enzyme may contribute to resistance to antiepileptic drug treatment 62

Waking up between 1:00 and 3:00 AM often a indicates a low blood sugar level but this can also be due to a combination of cortisol and sugar imbalances

Bayne S, Li H, Jones ME, Pinto AR, Van Sinderen M, Drummond A, et al

In clinical trials, doses are escalated gradually over several weeks to improve tolerability a process known as dose titration