Mangeot PE, Risson V, Fusil F, Marnef A, Laurent E, Blin J, Mournetas V, Massourides E, Sohier TJM, Corbin A, Aube F, Teixeira M, Pinset C, Schaeffer L, Legube G, Cosset FL, Verhoeyen E, Ohlmann T, Ricci EP (2019) Genome editing in primary cells and in vivo using viral-derived nanoblades loaded with Cas9-sgRNA ribonucleoproteins
The three-carbon sugar generated is glyceraldehyde-3-phosphate which can be shunted to glycolysis and oxidized to pyruvate
Abbasi J
It has Vitamin A and fatty acids as well
Disruptions in gut microbiota composition may exacerbate inflammation through the vagal nerve and the weakened BBB, establishing a feedback loop which accelerates disease progression 46