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Genetic variations in your GLP1R gene (such as rs6923761) can affect how strongly your cells respond to this signal, which is why some people lose weight easily while others struggle despite eating less
Dev Cell 2019, 51: 575-586.e4
However, its important to note that not all peptides are used as appetite suppressants, and the use of specific peptide-based medications would depend on factors such as prescription requirements and individual health conditions
The incretin effect is reduced in people with T2DM, mainly because GIP has less of an impact [85]
The long half-life provides a safety net for occasional missed doses, but optimal results require regular weekly injections
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