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INPP5B gene expression in the anterior cingulate cortex (BA24), hippocampus, hypothalamus, and nucleus accumbens was negatively associated with plasma protein levels, while CALCB gene expression in the cerebellum was positively associated with plasma protein levels
The beads were then subjected to tryptic digestion, performed with 5 L of 25 ng/mL trypsin and 45 L of 25 mM NH 4 HCO 3 on ice for 45 min, incubated overnight at 37 C
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Analysis of adverse effects (OR = 0.03, 95% CI: 0.030.09) revealed comparable safety profiles, with reported events primarily consisting of gastrointestinal symptoms (abdominal pain, nausea, reflux, diarrhea, constipation, flatulence, and indigestion), neurological effects (headache and daytime drowsiness), and occasional hypersensitivity reactions or cold sores
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