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To minimize these events, Sean Wharton, MD, director of the Wharton Medical Clinic in Toronto, and colleagues suggest the three Es: E ducation and explanation E scalation to an appropriate dose E ffective management of GI side effects. Patients should be counseled on means to decrease adverse event risk such as reducing meal size
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The products were dialyzed against 0.5 M NaHCO 3 for 24 h, followed by dialysis against deionized water for over 24 h
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