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At the same time, the evidence base remains limited relative to FDA-approved medications, the regulatory landscape is actively evolving, and the risk profile requires careful individual medical evaluation

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doi: 10.1053/meta.2000.6738 46 ZhaoJTCowleyMJLeePBirznieceVKaplanWHoKKY

This gives people a new option for managing their weight under medical supervision

The firm pointed to the extensive gross-to-net adjustments that the manufacturers are already providing on these drugs. BMO Capital Markets, for its part, wrote in a note to investors, We reiterate that the important comparison remains the difference between the products newly discounted price and the products ultimate net price, including rebates, instead of their list prices