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J Allergy Clin Immunol Pract 7(4):12531260 e1253 Jaffe HS, Abrams DI, Ammann AJ, Lewis BJ, Golden JA (1983) Complications of co-trimoxazole in treatment of AIDS-associated Pneumocystis carinii pneumonia in homosexual men
Its interactions with the vagus nerve have been investigated in the context of brain-gut axis effects, including gastroparesis (delayed gastric emptying), where BPC-157 has shown consistent pro-motility effects in preclinical models through vagal cholinergic pathways
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Warning signs requiring immediate evaluation include cold affecting only one leg, absent foot pulses, skin color changes from pink to blue or white, and leg pain that occurs after walking specific distances
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