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For the enzymes affected by estradiol in one-carbon metabolism (yellow enzymes), as estradiol varies during the menstrual cycle, the multiplier of the V max of the enzyme is scaled between the male value and the female value in table 3 in [22]

[116] identified five ferroptosis-related genes (DDIT4, MUC1, KLHL24, CD44, and RB1) as key contributors to AD progression

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