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Safety, tolerability, and pharmacodynamics of intrathecal injection of recombinant human HGF (KP-100) in subjects with amyotrophic lateral sclerosis: a Phase I trial
Plus, a 2020 meta-analysis of 12 studies found that berberine intake modestly but significantly decreased study participants body weight, body mass index (BMI), waist circumference, and concentrations of C-reactive protein (a protein produced in the liver in response to inflammation in the body)
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Inadequate Therapeutic Response: Contact your healthcare provider if you experience minimal or no improvement in target outcomes after reaching your maintenance dose for 12-16 weeks
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