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The SELECT cardiovascular outcomes trial (N=17,604) demonstrated that semaglutide 2.4 mg reduced major adverse cardiovascular events by 20% (HR 0.80, 95% CI: 0.72 to 0.90) compared to placebo over a median 39.8 months of follow-up (Lincoff et al., NEJM, 2023) [14]
Organ Function: Comprehensive renal function testing (eGFR) is absolutely mandatory to ensure the kidneys can safely process the drug
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Some formulas also include ingredients like niacinamide, vitamin C, licorice extract, aloe vera, glycerin, or hyaluronic acid
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