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Sources: Jastreboff AM, et al

Finally, based on changes in energy supply sources, L-carnitine regulates the utilization of glucose synthesis and fatty acid oxidation, providing the organism with a certain buffering capacity to cope with complex changes

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Moving forward, the most realistic near-term translational path lies in combining relatively simple, biocompatible bone-targeted nanocarriers (such as alendronate-functionalized liposomal or polymeric systems) to specifically co-deliver immunogenic cell death (ICD)-inducing standard chemotherapeutics alongside established immune checkpoint inhibitors (e.g., anti-PD-1/PD-L1) or myeloid cell modulators

Instead, we need to approach them with a more comprehensive understanding of their effects on gut health