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Patients must understand the risks inherent in GLP-1 therapy, including the effects on anesthesia, the potential for muscle mass loss, the likelihood of weight regain upon discontinuation, and the importance of honest self-reporting
It was the first breakthrough medication in this category
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This slow titration is often the safest way for someone with a sensitive gut to introduce a GLP-1 medication
insulin resistance/obesity (110, 116)
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