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Abstract Treatment with a nicotinamide N-methyltransferase inhibitor (NNMTi

Glutathione reduces oxidative stress on the liver as it processes medication and mobilized fat, which may lower fatigue and nausea severity

While patients require a medical history of MASH, liver biopsy might not be absolutely required for medication approval and may be supplemented by liver fibrosis imaging (transient elastography [FibroScan] or magnetic resonance elastography) and noninvasive fibrosis scoring (fibrosis-4 index)