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I think peptides hold a lot of promise but we really need human efficacy and safety data to guide therapies

GIP and GLP-1 have opposite effects on glucagon release with GIP stimulating glucagon release through an increase of intracellular cyclic adenosine monophosphate levels

Most adults are deficient

This may be especially beneficial for individuals focused on longevity, athletic performance, or recovery from burnout

While results from IV ALA studies are consistently positive, the picture is more mixed when it comes to oral-only supplementation: A four-year randomized trial found no significant improvement in a composite measure of nerve function with 600mg/day of oral ALA compared to placebo