If using topically, apply at night so your skin can absorb it while you sleep and repair overnight
Kraemer WJ, Volek JS, French DN, Rubin MR, Sharman MJ, Gomez AL, Ratamess NA, Newton RU, Jemiolo B, Craig BW, et al
Rat studies have shown that the peptide can both stimulate collagen production in normal skin and help degrade extra-large collagen aggregates in scar tissue, suggesting context-dependent effects that promote normalized tissue structure (Pickart & Margolina, 2018)
Timeline and Expectations Understanding realistic timelines helps set appropriate expectations and prevents premature discontinuation before therapeutic effects fully develop
However, broader guidance from NICE, the NHS, and the MHRA provides a clear framework for understanding how unapproved substances should be approached