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The SURMOUNT-5 head-to-head trial directly compared tirzepatide to semaglutide and found 47% greater weight loss with tirzepatide at 72 weeks
In the Fall of 2022, my weight approached 192 pounds, which is close to the heaviest I have ever weighed (2 nd only to my chief residency year)
At this low dose, many people have minimal or no symptoms
Semaglutide-treated mice lost 22% of their body weight, with fat mass dropping 46% and LBM dropping only about 4%
Real-world data from compounding pharmacies shows that patients with modest weight loss goals often experience success when they combine semaglutide with behavioral changes like structured meal planning and regular movement
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