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The outcome measures of interest include average drinks (Poisson distribution) and binge drinking (Binomial distribution) calculated from TLFB, AUDIT scores (Gaussian distribution), alcohol use per episode of use (Gaussian distribution) and the sedative and stimulative scores from the BAES scale (Gaussian distribution)
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Additionally, large-scale randomized controlled trials with longer follow-up periods are needed to confirm the cardiovascular benefits of GLP-1RAs in patients with T2D undergoing coronary stent implantation
In addition, many smart hydrogels are regulated as combination products that integrate a device-like scaffold with drug, biologic, cell, or gene payloads
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