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Retatrutide is an investigational triple receptor agonist (GLP-1, GIP, glucagon) not yet approved by the MHRA or EMA as of 2025
Starting our patients with semaglutide also allows us to evaluate how they respond to GLP-1 therapy alone before potentially introducing the additional GIP action with tirzepatide
These effects relate directly to growth hormone elevation and typically resolve with dose adjustment
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