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Bottom panel: 8-Isoprostane levels were reduced by 35% in the low dose group (gray bar) at week 2
Looking forward, the field is moving toward precision medicine
In addition, the generation of ROS by platelets, the absorption of free radicals from the environment, and the depletion of antioxidants can lead to pro-oxidant, pro-inflammatory, and platelet hyperaggregability effects, which increase the risk of CVD (178)
The bound toxin becomes water-soluble and is excreted through bile or urine
16 Once within the nucleus Nrf2 binds to a region of DNA known as an Antioxidant Response Element or ARE
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