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The blood pressure-lowering effects likely result primarily from weight loss, which reduces cardiac workload and peripheral vascular resistance , leading to decreased blood pressure through hemodynamic changes
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S., Venzon, L., da Silva, L
Tirzepatide differs from other weight loss medications because it mimics two incretins, GLP- 1 (glycogen-like protein) and GIP (glucose-dependent insulinotropic polypeptide) receptors, while others only mimic one incretin (GLP-1)
Surprisingly, intervention longer than 24 weeks showed no significant effect on BMI [40]
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