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Several animals studies have found that GLP-1 agonists can reduce drug and alcohol seeking behavior, but there isnt strong data from human trials: one small trial found that GLP-1 agonists could reduce opioid cravings, for example, while another found they could reduce cravings for alcohol, but only in people who were living with obesity
Your actual dose should be tailored by a licensed healthcare provider
Usage Comparisons A 2023 study published in BMJ (formerly the British Medical Journal) suggests tirzepatide the active ingredient in Mounjaro may outperform semaglutide in weight loss efficacy
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In addition, GLP-1R overexpression results in improved cognitive function in mice and GLP-1R knockout severely impairs cognitive ability (5, 117, 118)
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