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[2] Once administered intramuscularly, B12 is gradually released into the bloodstream and transported to the liver, where approximately half of the body's total B12 stores are held

Vitamin B12 should be supplemented in vegetarians who do not get adequate amounts of B12 from diet or patients consuming a low calorie/low protein diet

I generally take a magnesium/potassium combo supplement, along with folate (400 to 800 mg a day) , and vitamin D

[106] Other drugs [edit] Certain medications can decrease the absorption of orally consumed vitamin B 12 , including colchicine, extended-release potassium products, and antibiotics such as gentamicin, neomycin and tobramycin

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